Statin Adherence Affects Likelihood of Death

Share This Post

Share on facebook
Share on linkedin
Share on twitter
Share on email

A link between the risk of dying and how often patients take their statins was identified by a large observational study. The researchers looked at how poor statin adherence affects mortality in patients with atherosclerotic cardiovascular disease (ASCVD). They identified almost 350,000 patients with documented ASCVD who were getting ongoing statin prescriptions. A “medication possession ratio” (MPR) was calculated for each patient to assess adherence. MPR is calculated by dividing the number of days of statin supplied during a 12-month period by the number of days that the patient was not hospitalized and alive during the period. About 25% of the patients died during an average follow-up period of nearly 3 years.

Patients who were taking statins less than 50% of the time had a 20% increase in mortality compared with those taking them at least 90% of the time. Women, minority groups, and patients younger and older than the age range of 65 to 74 years were the least adherent.

For patients on statins, it is important to check in regularly on adherence – ask them if they take their statin every day.

• Rodriguez F et al. JAMA Cardiol 2019 Feb 13; [e-pub].

More To Explore

What is The Rx Consultant?

The Rx Consultant is a subscription-based service that delivers practical updates & reviews covering all the top-selling drugs and common health conditions. All our publications focus on the facts busy front-line pharmacists and other health care practitioners need to stay current, and provide it a streamlined, easy reading style.

For 30 years The Rx Consultant has operated independent of the pharmaceutical industry and has no commercial bias.

Join thousands of healthcare providers who enjoy the following benefits every month.

1. Drug Therapy Updates & Reviews

The eLibrary contains over 30 streamlined updates on drug therapy for the most common diseases. New articles are added every month – it is a continually expanding resource.

2. Continuing Education

The eLibrary includes 50+ hours of Pharmacology CE from an ACPE approved provider at no additional charge. Each article provides at least 1.5 hours of Pharmacology CE. Subscribers can take their tests online, score them immediately, then print or save their credit statements. Pharmacology CE tests can also be mailed, faxed, or even phoned in to The Rx Consultant office, and credit statements will be delivered by mail or fax.

3. Unlimited Access to our Resource Library, with:

  • Healthcare News

    The eLibrary includes a news column covering the developments that matter most to nurse practitioners and other front-line providers. You get a headline, the bottom line, and how it’s likely to affect your practice in a few short lines, then it’s on to the next news item. The news briefs are also available in print monthly as Rx News Connection.
  • Patient Education Pages

    Patient Q&A to sharpen your skills in educating patients and answering common questions.
  • Charts & Tables

    At-a-glance updates on drugs, doses, common side effects & interactions
  • Quick Facts

    Key facts organized for fast access both online and on handy reference cards.
  • The Bottom Line

    Our members suggest the topics and each issue undergoes a rigorous three month peer reviewed process. Our CE is different because we accept no grants, advertising, or funding of any kind from drug manufacturers. With no financial ties, maintaining a bias-free publication is a straightforward process.

The Rx Consultant maintains a high standard for quality

And a rigorous system for content development that insures it. Every issue is written by an expert in the topic area, and then peer reviewed, fact-checked and edited to insure that the content is

  • Evidence-based
  • Non-Biased
  • Balanced
  • Timely
  • Accurate and
  • Useful for community practitioners

The Rx Consultant is completely independent of the pharmaceutical industry.

We accept no grants, advertising, or funding of any kind from drug manufacturers. With no financial ties, maintaining a bias-free publication is a straightforward process.